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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64449177cad14e0ad83ac0607549a0bc5164d8424d6cf399ef64ca17ebc98e7c' 
  AND token = 'hVBkbrCN+iTt5mGZwiwcsbDfkGQFRXSiC0Uz2CTlVOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}