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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '224f8ca48aa814453e79cd0a7ed089f7825f99b1509e6c5c08e53a92bdae5ae8' 
  AND token = '8vvfdpudMU/yxrhX8InRR3aMdlbDtLyDzqRxFzeAQhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}