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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b221ee8b74d4327205b5f634130ae1d09fa176cc803323b2b2edd47bfe3ca8d4' 
  AND token = 'Rhmt+DfVAv+FBpXfRgPFVXV73iRFS2NGYD9yHn6DTHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}