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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f4fce4fc5f1094de0c57c88696b0e720b5c35413155bcd167d1a5ded031c100' 
  AND token = 'b5pFf1dtPJfMI/9xQdv0HyogZPRTzxhz84pqBHES13E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}