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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '253f4acf57393b304a0fffae9734817b6a1689307ad764e163292f5c94f1140d' 
  AND token = 'NZS4AA8ggyY70bOvrm73GIzROEDyuDJu2DwFl23kZaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}