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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aa9fe1434017bc121b878875f196d6335f88f700f13b2df5548c304eeace369' 
  AND token = '+WwzlO8FT3jTK+vZcSfo8cCLpCW+t7ZZ/XiFkH5ha4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}