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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8a5daad0b7f91b67d3aeb723a74a3cbc8a05739ecac01805efdf13340f38f46' 
  AND token = 'tV/sNyA9Y8BwPejfdJfuW+LN6t1li//PPV2s+Iw4fOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}