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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '478c16fdce35fa598585757124b37314f854dedf2fcf39b97536d26c0adb47b3' 
  AND token = 'n8DZGSDoipq8fqCWNl1KK+aezfJA2LqNn5eL5JWAvic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}