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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '343ca873f822e9a3f804dfa6e6ec2250bb8b6dae1370134c4a71dd3247cda899' 
  AND token = 'gAIZEjj4OkUuF1y6kmmq/v0bK1HPOqtVrCRMXcpScs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}