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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f219ddf11e196e05254e3b643b18e01c17eb1cec10d9abdf299deba8ab9c50d1' 
  AND token = 'nYxat0VlV+mTr0ALf+ceysU+kZROQdzkgWTaKNgQsA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}