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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c57316f150886b08b457d8d2309ddbc54dc321f03670abc94709212d15b14d30' 
  AND token = 'I667CP0Dd1bxekKwH1Sa+hu+gs1G1vxxQqpBZTJ26E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}