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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d9edd7ad83f53feb78f0876421fcd0c44adc996012fcd95acbb1b929bd00ba' 
  AND token = 'VQQDrzMDT3nqKOfjb77Ba9U2VC8S5v7NKXdDy4kM1O0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}