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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c7e99e845a530aa7b4f9369197d1e5a2b6222d3856bbfe5827efaaa2777d399' 
  AND token = 'O7WqQ6cV5SzKv6qHnioajZQ6B1Sjfg3cys461nrXgDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}