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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab2d1f0e2ad13df77786fc504d00be85ccbf4a2100f929a80e59147127f72677' 
  AND token = 'IcCk/HrXB4NI2Vx2EBKvEL4bnMJKjHxr00nSnp/dxgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}