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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cdb1933db9f87a0ab22e998aa68af3b97d6e26aecd4db36cda05d00b722e3c2' 
  AND token = 'rF0QDig8gXy23D55QWppedskDgDksrFgNHVG+f6HSw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}