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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cfb8c535689522907e3eef9a9039a01614cf96a2f6dd581770dee7e9f1826e3' 
  AND token = 'kqruqZob52Pgu8TO+0sS/pKS6Kik2qlnOSgu5mTCCCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}