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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7382a39b5271d139d6c412c7da92d2d75cfd0dae391e606efcbebb169735c9f3' 
  AND token = 'x9uPZD399EmiVJDjW2KP3VvG+6x/TEdMgAKrEfxGk9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}