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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '435fe681c9fbfd823e16dedbf880590c8352c594b9a46f53bb536ca9579d7efe' 
  AND token = 'BSr7WR+l5kRnQQeaBArFEDjFpqmuzqNkMXTeGzO392s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}