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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b6878ebbf3aa770b8b2087542aa6fb661ad175222a286720d196279a0c3a750' 
  AND token = 'w7OjkLpBREc5D7FXO3da/phjJG6BUQSc91u0Ew4mv6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}