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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '617c9b3246d25b8977b13aa3c83c6e6618812d2b563e28d9d911bf35aa274ded' 
  AND token = 'UPJMkJVtwIxNyYIFiYk+NGk71ADdrfbDCPFlgj2XrL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}