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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3df0452157a6ff1df7eb7c934cff3318195d4206a568d85bb7f50aad48026b45' 
  AND token = 'B9RXPztt+p8HxJsmpp5Af9wwJN1EzQXaa96vf7Bs3WM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}