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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c6e6fa1712499097c00c7c0e7058d3eb66226bee92a9cd071b6b42a57def607' 
  AND token = 'Q+J3OyRQQAAgCv7KtTGvPTEEKC8Gw4KwvZraRGsV8gI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}