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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '299f2d601aca367d0f495e0e0767728a953f51f2e283028f35a4d33292329841' 
  AND token = 'Pg++spkeDti31N5X6ACSoVWymr88KLreKSy26vZSrQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}