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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00ef08633868bd61e3518f5dca8d14b1fdb5a50824e2d8f892b72a9e9fcb4678' 
  AND token = '9YN4dWNDb2jkFpCLr4g57aOZNw8wSJ0T/nPB55ehUJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}