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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2ae5ad60c0a501797369bf0ad66f67ab48a6bd69f4686975d658216510ba130' 
  AND token = 'KREdZlWSqDrI20vdWIPl4Hu2yqara2IilXGPVWYZfsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}