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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e22e0e028174b4010003a6cfaa0fb0f7fe25c03d1c86287940ea0ff1429e2a7' 
  AND token = '4S5eisjmfdZOaHhx5JvJ3pJD3+KvyBNKlbiBMWTU334=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}