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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5050862bb1f38c9e6e806698e71ac7067fdadcd4c18d0082ffc4f5cfaf37d94a' 
  AND token = 'XIgnA7zLg5lTCOGTO832Hwl98/KPMnQjlvSk7LjY5j8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}