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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '577b281287ef98b26901e50ae045258946226cca89ee3892f662a1c81df95231' 
  AND token = '/09kJellJO8MZrA/t0lEmJwZRPF67OU/YLsRUyY931A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}