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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b37f050e93a938354a0f2edf53633fbd8d095ea40d7a5b9722c2f348a1e0d00e' 
  AND token = 'jCKFitq072SpJob2eNJMMtYcWQ7KNY8P1R1ixUTYlOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}