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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eed653490884d6857082659b1a95e241128f95aad72298798c90a15523c6f12e' 
  AND token = 'MrPP5HAObRZ5CgX/HhEJmE13wXYsHLO6p076m9oeWuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}