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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '579f76e6d843bacb60838f920ad02b0f81ccfd12b63ef8535ab744c458504276' 
  AND token = '+SvO15iWWYWZ7V3dlNfCYccrPwkH3MACJUyzQXE4Ca0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}