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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ccc0728d4d50a27be05fa47e89fc7bb40482c710c51e218e6deb64e359a9382' 
  AND token = 'h6YV2MhFfPPIldPdV2tAF0Qen/dkzzi1LW40Mq+VZg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}