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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4671210c9a1f49168fd30b87b02e8248f41fc9ed7cde32e77f799b6e115f4d67' 
  AND token = 'B1CYpo8rLy1nzmIUCRPr/7QR65WRxY9Vm7FoVrWPVwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}