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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1557d3efa09ac4035c2f9d409e74422ec72353deb01ac7085f18977e24075c7b' 
  AND token = 'smtPFkoIA16xeKM6Md2JMm8TqcO/0gJqW17ACmZrWJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}