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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e07d8b6323455425f4714e2a41d40954a4669d6f6a29138ebdfee3fa662c1431' 
  AND token = '3DdUmNpEi63FAbdmUPXwIoE77NzqXqoibwC9XtlVtnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}