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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f9ca46b1f4a0cb0932f70246c626003c84cb6ae96a5e5aff0c49dd09c6d7b87' 
  AND token = 'otfdk1vnWBFg87K0H5NODqnupp6dL9Vzlz47LjJg31Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}