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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34402f5248a2986a1072c2cb8c0e4ca2bceb635958146ed42692a2c4f71ac2e2' 
  AND token = 'lPXo/u0RM0MRzLGhyhwK6iyfQHSiOgdVzkkD1tqoF8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}