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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c1e3acbfe118695c542604d2bbe1be5c954c008b26d9ce39d50fea2088795cf' 
  AND token = 'iz9UCB8gnaK4Ws38ti8b5U04fYBYYUC2jfNP9CjVMk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}