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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8793b7bfa89fbd5daad0869bd4a45d1e702754d0f28f0e359b9e683e46142234' 
  AND token = 'sM4MPJdCTEc8gNoLTxzuwFUNPZ0lphAwSSDrUbOw8l0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}