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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0382cb8ead7d0c20181a1688ca1a03a78cb6a51afc0ee7ca01b9d7183f6fb339' 
  AND token = '9VB9u65aStjzCXj8aWL18fz97WwcvRAetu1PEjIqBJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}