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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50867de3326c7c7d00d6f128c3783b8d9822c5c1756d2d13d8ea1111b8ae6a4d' 
  AND token = 'UPEwaeSX2bR4QIYuKeIUBXvCtlqATA4uNQEDLOQOIdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}