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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89e6b9a265ac1de6857c26e6d6c74a0beb7de9cafcc72f19e5999414853737fc' 
  AND token = 'i1AO0mmELHTc0MAQAsaPcVYMrIGzd6SbDxIkW+iUlEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}