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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49d04cd1dac2554e68a63299fabceeb58efb5fe3d5390eb064bf0269a53cf968' 
  AND token = 'DrJXv+d9pJTePu5rcETHz5CzCAiWu4BwntK+1BA8zoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}