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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cdc0a66045af56b2756c17d6f4c08dfab7f5b5cd81d4b39c69769038480fc4d' 
  AND token = 'LMduY1MUw5LN8m5nLuj8sSneQdt+UWyrSJKUd16/OLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}