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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a42012e4f4006053d32844d35c3f1e5437254291df60e49c12d4d40acf55936c' 
  AND token = 'LxoPLk1XUuOJ8RXYC8vTJK0lxPDi0uAXm3Lfyi6nNkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}