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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d8c02ba28f3f4629783628e055d82e9c3d4fb73de589e090a4bb889b747f4b1' 
  AND token = 'PegXd9/nKkfUWPGXdKbC2NRAB3O518rsV4/pW4xjKSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}