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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549f4c4488f5c64a2411afc5eec2ba8bcb85b1a512c1eb33ecad4c9a17281f6d' 
  AND token = '5d6Wm/lq2HpLPSv4/vlP5YwHvuH3sO1jqTrUL/O9j8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}