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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f65f420fa754499270d204f20bc9a0130bc2e1d0bcbcd8d61e8b4d0c5a9517e1' 
  AND token = 'TfQiWFsLgR06XJMuwvi/B6PQxQDT3kf4ekaXOKwT3v8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}