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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b3ed3c634644bd378e00a52d22386960748acbe66c467a9e1d718f60845d502' 
  AND token = 'gDq9vzAyoItjzb9eeEbFEj4W8FlbFexjz74kATO00ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}