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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '796d8247c8aebb69da35edcf8a2b6dd2fc186f286b12b397f1b2314861d274d5' 
  AND token = '4Za1tIerLcup1t9+02V/OacrIFB7rw+9krqSkwgw34U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}